The one-way fares will be available on a first come, first served basis from 9am on March 22.
There are 99 tickets priced at £99 available on each of Primera’s four North American routes: New York, Boston, Toronto and Washington DC.
The carrier’s London-New York route will launch on April 19, followed by Boston on May 18.
Primera will then begin flying to Toronto a day later on May 19 and Washington DC on August 22.
The Nordic airline has been established in Northern Europe for more than a decade and its North American expansion marks the first time it will fly from the UK.
Primera’s £99 one-way fares are available on the ‘Light’ package which includes a seat and 10kg hand luggage and are valid for travel between April 19 and December 9.