Jet2.com and Jet2holidays has confirmed it will be making redundancies following a review of its operations in Spain.
The airline and operator is understood to have around 1,000 staff based at airports in Spain and its islands.
Jet2 currently flies to six destinations in mainland Spain, including Alicante and Malaga, four in the Canary Islands and three in the Balearics.
According to local media reports in the Canaries, Jet2 has entered into a 30-day period of negotiations with union officials in Spain, which could see up to 35% of affected roles made redundant.
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