Sailing between 20 February and 21 June 2022, the vessel will visit 32 ports in 12 countries, including Norway, Spain and Portugal.
The programme also includes six overnight port calls and three late-evening departures.
A call in Amsterdam on a four-night short break brings an opportunity to explore the city’s canals by night while other highlights include Genoa, Ibiza, Manzanillo, Grand Turk and San Francisco.
Cunard president Simon Palethorpe said the new programme has "something for everyone".
"We’re thrilled to offer this exciting new escapes programme to guests who might long for a voyage that promises a sense of freedom, luxury and style," he added.
The additional voyages include a 14-night Canary Islands itinerary with stops in Cadiz and Lisbon with an overnight port call in Madeira. Departs Southampton on 20 February with fares from £899.
A 12-night Norway and Northern Lights sailing departs Southampton on 18 March and costs £1,099.
The four-night Amsterdam cruise from Southampton calls overnight in the Dutch capital and prices come in at £449, while a 17-night Western Mediterranean sailing, also from Southampton, departs on 15 April and costs £1,499.
The 12-night Westbound Transatlantic Crossing includes an overnight stay in Port Canaveral. Departs Southampton on 2 May. Inside staterooms prices start from £799.
A 43-night Panama Canal and Alaska voyage offers trips to Grand Turk Aruba and Alaska. Fares start from £2,999.
Queen Elizabeth’s new itineraries were available to book from Thursday (18 November).
