Flight EK034 will then depart for Dubai at 9.10pm, arriving 7.25am on Saturday (16 October).
The Newcastle resumption follows the airline’s restart of operations to Heathrow, Manchester, Birmingham and Glasgow airports over recent months in response to a reported "surge in demand" for international travel.
The Newcastle service will operate four times weekly and will take Emirates’ total UK weekly flights to 77.
Richard Jewsbury, divisional vice-president at Emirates UK, said: "We’re extremely pleased to see flights returning to and from Newcastle, responding to an increase in bookings across the UK since international travel was made far simpler.
