The carrier will operate a weekly Saturday service to Innsbruck from Birmingham, Manchester and Stansted.
Birmingham and Manchester flights will operate from late December to mid-April. Stansted flights will operate from February to April.
Tyrolean capital Innsbruck hosted the 1964 and 1976 Winter Olympics and serves a wide range of ski resorts throughout the Austrian Alps.
Jet2 will also add weekly flights from Manchester to Verona and East Midlands to Grenoble.