Some 377 departures were cancelled between 25 May and 31 May, new data from aviation analytics firm Cirium reveals.
The remaining 18,330 made it away as scheduled.
EasyJet flights were worst affected, with 249 of the 377 cancellations – two-thirds (66%) – being easyJet departures.
There were also 19 Loganair cancellations, 16 British Airways (including BA CityFlyer), 15 Eastern Airways and 14 Tui.
Gatwick had the most cancellations (151), followed by Manchester (41), Heathrow (36), Bristol (27) and Edinburgh (19).
Nearly 11,000 flights are scheduled to depart the UK over the Platinum Jubilee bank holiday weekend (2-5 June).
