The budget carrier will base two aircraft there, flying 11 routes to seven countries.
The move represents an investment of $200 million and will create 60 new Ryanair jobs and support 750 airport jobs.
Ryanair says it will transit around a million additional passengers through the airport.
The new routes are: Alicante, Brest, Budapest, Lille, Luxembourg, Marseille, Oujda (Morocco), Palermo, Porto, Tangier and Valencia.
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