The ship will operate a Splendors of Egypt and The Nile itinerary, which includes four nights in Cairo at the beginning and end of the sailing, all meals, wine, spirits, excursions, airport transfers and onboard gratuities. Prices lead in at £5,129pp.
Sphinx features a private dining room, an alfresco experience on the upper deck, a swimming pool, massage room and 42 suites.
Ellen Bettridge, chief executive and president of Uniworld River Cruises, said the line is "overjoyed" to sail along the Nile river and provide "an unmatched look at the destination".