On Monday 7 November and Wednesday 9 November, the RMT union has voted to strike on National Rail services, meaning services into Central London will run on a drastically reduced timetable.
However, Transport for London (TfL) services – including London Underground, London Overground, the DLR and the newly opened Elizabeth Line, will operate as normal.
Juliette Losardo, exhibition director for WTM London, said it was "disappointing" the action was called on the first and last days of the event.
"National Rail services coming into the capital will be affected, but Transport for London services are operating as scheduled," she added.
"ExCeL London is a world-class venue with infrastructure to remedy issues such as these. If you’d normally rely on National Rail services, consider local accommodation, or utilise ExCel London’s car parking facilities.
"Over the past few years our sector has navigated far worse, and we’re confident the travel community will be out in force."