The upgrade, scheduled for spring 2027, will last 39 days and will see the ship fitted with new Grill Suites accommodation, an elevated wellness offering, and refreshed retail and guest spaces.
The ship will enter dry dock at Damen Shiprepair Brest in France, on 31 March 2027 and return to service on 9 May 2027 after the refurbishment has been completed.
Thirty-one new staterooms will be added across the ship, including 16 new Cunard Princess Grill Suites, with the remaining 15 new staterooms in the Britannia category.
Every existing Grill Suite will be refreshed with new interiors, updated furnishings and finishes. Newly designed bathrooms will be introduced across all Grill Suite categories, with a sophisticated new look and premium spa-inspired features.
The Queens Grill and Princess Grill restaurants will also be refreshed to "ensure they continue to offer the same sense of space, comfort and exclusivity", according to Cunard.
Guests can enjoy additional outdoor deck space, with places to relax, watch the sunset and take in the sea air. Classic deck games along with paddle tennis and pickleball will continue to be part of the Queen Mary 2 experience.
Queen Mary 2's famous kennels will also be enhanced. Improvements include redesigned kennels, increased capacity, a refurbished owners' lounge and an expanded outdoor walking area, further elevating the experience for guests crossing the Atlantic with their pets.
Mareel Wellness & Beauty will be transformed as part of the refurbishment, creating an updated space. New luxury stores will also be introduced, bringing a boutique-style shopping experience to the ship, the line added.
Illuminations, the largest planetarium at sea, will receive a major digital upgrade, delivering more immersive, state-of-the-art experiences beneath its dome.
Cunard President Katie McAlister said: “Queen Mary 2 is more than a ship, she is an icon of modern luxury travel and the only true ocean liner in the world.
"This is a significant investment in Queen Mary 2, and every decision has been approached with deep respect for her heritage, her character and the sense of occasion that only Queen Mary 2 can offer. We are not reinventing what guests love about her; we are refining it beautifully and ensuring she carries it forward.”