The line said the stands at Bluewater in Kent and Westfield in Shepherd’s Bush, west London, "will bring to life what a guest can experience on a P&O Cruises holiday".
The stands will showcase the destinations the line calls into and feature a sensory lounge where visitors can "explore more on tablets" about P&O Cruises products.
Visitors will also have the chance to enter a competition to win a P&O Cruises holiday.
The pop-up stands will be in Bluewater Shopping Centre’s Moon Court from 27 January to 9 February and in Westfield Shopping Centre’s North Atrium from 19 February to 3 March.