The first flight on the route since March 2020 took off on Thursday (12 May).
It is the latest in a series of North American route restarts for Aer Lingus, with its Seattle and Miami services due to resume later this year.
One-way fares to Los Angeles lead in from £269pp, including taxes and charges.
UK travellers will benefit from US Immigration pre-clearance for flights to North America via the airline’s Dublin hub.
UK customers can fly to Los Angeles International airport via Dublin airport from Heathrow, Gatwick, Birmingham, Bristol, Manchester, Leeds Bradford, Glasgow and Edinburgh.
