BA will begin the service between Oakland and Gatwick on March 28, and another service between Gatwick and Fort Lauderdale on July 6, competing with discount carrier Norwegian on both routes.
BA’s new Oakland route will be its first from Gatwick to California, and its fifth service from London to the state.
San Francisco which is a 30-minute train journey or a 35 minute drive by car.
The route will be served by a 777-200ER aircraft operating four-days a week, with flights launching from £189 each way.