The two carriers’ first codeshare flights are now live, offering new connections to the north of England and Scotland. The partnership was first announced in July.
Initial connecting destinations from Guernsey and Jersey include Edinburgh, Glasgow, Newcastle and Manchester, via Southampton.
Meanwhile, from Exeter and Southampton, passengers can fly to Aberdeen and Inverness, via Manchester.
These flights will start on 26 October.
Codeshares allow customers to book connecting flights seamlessly via one booking and transaction, with luggage checked through to their final destination.
Blue Islands chief executive Rob Veron said: "Our initial set of connections enable easy travel to a number of very popular destinations in Scotland and the north for our customers in Guernsey, Jersey, Exeter and Southampton.
We expect the network to develop even further very soon, with a wider choice of destinations for next summer.”
Loganair chief executive Jonathan Hinkles added: "We’re confident it will be welcome news for customers looking to travel to the north from the Channel Isles and by those in Scotland looking to explore all that Jersey and Guernsey have to offer.
"The agreement also greatly strengthens our connectivity to Southampton and Exeter with extra connecting options via Manchester complementing our direct services from the central belt and Newcastle."
