The final 747 – a 747-8 cargo aircraft – rolled off the production line in Seattle late last year.
It will be delivered to Atlas Air on Tuesday (31 January).
A ceremony is due to be held at the Boeing factory in Everett, Washington state, to mark the occasion, and is expected to be attended by thousands of current and former employees.
While the global fleet of 747s will continue to fly for several decades to come, the day marks the end of 54 years of production of an aircraft credited with democratising air travel.
