The vessel will commence its inaugural season in November 2023 with 17 Caribbean and Mediterranean voyages, plus two transatlantic crossings, all ranging from seven to 16 nights in length.
Designed by Studio DADO, Seven Seas Grandeur will be able to host 750 guests with a gross tonnage of 55,500.
Jason Montague, president and chief executive officer for Regent, said the vessel will be a "culmination of Regent’s rich history of providing discerning travellers unrivalled experiences with every imaginable luxury included".
"We are delighted to once again be in the hands of the talented engineers of Fincantieri, who will produce a ship of refined style, matchless elegance and breath-taking beauty," he added.