Passengers on a flight from Heathrow to Newark will use the CommonPass system from Wednesday.
CommonPass is backed by the World Economic Forum and designed as a register of those who have tested negative for Covid-19. Passengers are tested up to 72 hours before travel and upload results to their mobile phone.
They then complete any additional health screening questionnaires required by the destination country.
Cathay Pacific is also involved with CommonPass and is testing it on flights between Hong Kong and Singapore.