The weekly Saturday flight will offer 45% more capacity than in recent years due to demand for domestic breaks.
Roger Hage, the airline’s general manager, said: “Eastern Airways is all about supporting the regions of the UK, connecting people and places, so commencing Jersey will offer a welcome UK break destination from Humberside.
“Given recent new leisure additions such as Gibraltar from Birmingham and Southampton and Newquay from Leeds-Bradford, both restoring and adding further services at hubs we already serve are another crucial part of increasing connectivity and aiding economic recovery.”