As well as the 2050 goal, the airline has also set an interim science-based target for 2035. It plans to present its net-zero roadmap in the coming months.
In 2019, easyJet reportedly became the first major airline to offset the carbon emissions from the fuel used for all of its flights.
The airline said it was "optimistic" that it could begin flying customers on planes powered by hydrogen-combustion, hydrogen-electric or a hybrid of both by the mid to late-2030s.
The carrier currently operates Airbus NEO aircraft, which are said to be 15% more fuel-efficient than the planes they replace.
Johan Lundgren, chief executive of easyJet, said joining the campaign was a "major milestone" in the airline’s net-zero journey.
"Climate change is an issue which we all have to tackle – including us at easyJet," he added.
"We have a responsibility to minimise the impact of our flights and we are working very hard to make this happen; from efficient flying and fleet renewal to being the only major European carrier that is offsetting the carbon emissions from the fuel used for all its flights on behalf of all its customers."
He said easyJet’s ambition is to "ultimately achieve net-zero emission flying in the UK and Europe", and the company is working alongside industry leaders to help support zero-emission technologies for passenger planes in the future.
Aviation minister Robert Courts said easyJet is "stepping up to the challenge" in tackling climate change.
“Cop26 represents an opportunity to build momentum in reducing aviation emissions, particularly ahead of the next ICAO Assembly in 2022," he added.
