The Gulf carrier will deploy larger Airbus A380 aircraft on the route instead of Boeing B777s, offering almost 50% more capacity than planned.
It will offer three classes, First, Business and Economy, with flight EK015 scheduled to depart Dubai at 7.40am on 10 December arriving Gatwick at 11.40am.
Return flight EK016 will depart Gatwick at 1.35pm arriving Dubai at 12.40am the following day.
Richard Jewsbury, Emirates divisional vice-president UK, said: “Upgrading the Gatwick route to our A380 will help us meet ever growing demand for international travel from the British public.
"Whether it’s winter sun trips to Dubai or passengers travelling further afield to reconnect with family and friends, future bookings continue to gather pace.
“Gatwick airport has long been a valued partner for Emirates and we look forward to welcoming passengers back onboard Emirates’ flagship aircraft soon.”
From 10 December, Gatwick will become Emirates’ sixth operational gateway in the UK after restarting flights from Heathrow, Manchester, Birmingham, Glasgow and Newcastle.
By the end of December, it will offer 84 weekly flights between the UK and Dubai, with onward connections to more than 120 destinations – around 90% of Emirates’ pre-pandemic network.
The Gulf carrier is operating six-times-daily Heathrow flights to Dubai, double-daily Manchester flights, 10 weekly Birmingham services, a daily Glasgow service and four weekly Newcastle services.