The singer, songwriter and producer will appear on Iona’s Spain, Portugal and Canary Islands cruise from Southampton on 18 March and a Mediterranean cruise onboard Arvia departing Southampton on 30 April.
There will be two performances on each cruise and all proceeds from ticket sales for the shows will be donated to Child Bereavement UK and Teenage Cancer Trust.
Barlow, who is the music director of Arvia and Iona’s The 710 Club, said: "Music has been such a massive part of my life – and taken me on so many journeys and adventures.
"After some incredible shows with P&O Cruises last year, I can’t wait to perform on Arvia and Iona in 2023 and pass these experiences on to all the guests."
