Passengers travelling with American Airlines, Delta Air Lines, Emirates and Virgin Atlantic from Terminal 3 will be able to take advantage of the free service.
Travellers will be able to book a designated time and entry slot at security, with a view to reducing wait times and allowing Heathrow to more efficiently deploy resources.
The Heathrow Timeslot trial could be expanded to further airlines during the six-month windows, with outcomes informing any future extension of the initiative to other terminals.
Mark Powell, Heathrow’s operational planning director, said: "We’re constantly thinking of innovative ways to boost the safety and streamline the experience for our passengers.
"This new trial will give passengers that extra added bit of certainty and reassurance ahead of their journey and we think it will be particularly popular for those with families or nervous travellers who may want a bit more confidence in their journeys.
"We look forward to seeing the data come in to give us some learnings on how we can roll this out more widely across Heathrow.”