Flights will operate in winter from Birmingham, Leeds Bradford and Stansted airports for the first time since the same period in 2019. In addition, the companies have also extended the season to Malta from Manchester airport.
The extension means the airline and operator are offering services to the destination up to 28 November, with flights starting from March 2023 with around 6,000 extra seats going on sale.
Monday services from Birmingham have been extended to 28 November and restarting from 13 February 2023 and Wednesday services from Leeds Bradford will operate from 1 March 2023.
Thursday services from Stansted have been extended until 24 November 2022 and will restart from 16 February 2023.
Elsewhere, the companies will offer up to two weekly flights on Thursdays and Sundays from Manchester in November and March. Thursday services have been extended to 17 November 2022 from the base and will restart from 2 March 2023.
Steve Heapy, chief executive of Jet2.com and Jet2holidays, said the companies have seen "strong and sustained" demand since the return of international travel.
"As always, we have responded to that demand by extending the season to Malta from Birmingham, Leeds Bradford, Stansted and Manchester airports and offering flights up to the end of November and restarting again in March," he added.
"With customers continuing to jump at the chance to book and travel on their well-deserved holidays, we are confident that these new services to Malta, coupled with our award-winning customer service, will prove very popular."