The airline and operator will serve Sicily from five of its UK bases, Birmingham, Bristol, Leeds Bradford, Manchester and Stansted, flying to Catania.
It will also offer flights to Olbia in Sardinia from four bases – Birmingham, Leeds Bradford, Manchester and Stansted.
Catania opens up resorts on Sicily’s east coast, including Taormina, Taormina Mare, Giardini Naxos, Syracuse, Cefalu and Campofelice Di Roccella.
The island is the largest in the Mediterranean, and is both a popular beach and city break option, with Mount Etna serving as a spectacular backdrop.
Olbia, meanwhile, gives Jet2 customers access to resorts on Sardinia’s east coast and the Costa Smeralda.
These include Porto Cervo, Baia Sardinia, Budoni, San Teodoro, Cannigione, San Pantaleo, Orosei and Pittulongu, while Olbia is a popular city break destination.
City breaks to both Sicily and Sardinia will be available through Jet2CityBreaks, offering a range of mainly four and five-star accommodation, and villa holidays via Jet2Villas.
The additions grow Jet2.com and Jet2holidays’ range of Italian destinations to seven in total, with Sicily and Sardinia complementing Naples, Pisa, Rome, Venice and Verona.
Steve Heapy, Jet2.com and Jet2holidays chief executive, said: “We are continuing to see a great deal of demand for summer 2022, so we are adding Sicily and Sardinia to our programme to give customers and independent travel agents even more choice.
"These two stunning Italian islands offer holidaymakers everything from culture and history to sun and glamour, and we are going on sale with a fantastic choice of flights, resorts and hotels.
"This means we now have seven Italian destinations on sale for summer 2022."
Jet2’s 2022 Sicily (Catania) programme runs:
- Birmingham – weekly Wednesday services operating from 4 May to 26 October
- Bristol – weekly Tuesday services operating from 3 May to 25 October
- Leeds Bradford – weekly Wednesday services operating from 4 May to 26 October
- Manchester – up to two weekly services (Tuesday and Saturday), with flights operating from 30 April to 29 October
- Stansted – up to two weekly services (Wednesday and Sunday), with flights operating from 1 May to 30 October
Its 2022 Sardinia (Olbia) programme runs:
- Birmingham – weekly Sunday services operating from 29 May to 30 October
- Leeds Bradford – weekly Wednesday services operating from 25 May to 26 October
- Manchester – up to two weekly services (Wednesday and Sunday) operating from 1 May to 30 October
- Stansted – up to two weekly services (Wednesday and Sunday) operating from 1 May to 30 October