The move comes ahead of the vessel’s UK sailings in a bid to manage "prevailing risks" imposed by the virus.
It includes additional testing of both vaccinated and unvaccinated guests and crew, which allowed the line to identify suspect Covid cases at the terminal during the pre-embarkation process and onboard the ship.
All cases have been identified and "effectively managed" in line with the protocol and in cooperation with relevant UK health authorities.
An MSC spokesperson said: "This is yet another example of our protocol doing exactly what it was designed to do. The MSC Cruises health and safety protocol is designed to keep our guests, crew and the communities our vessels call at safe, and its measures are sufficiently robust in the face of the current circumstances."
