The episodes, which will air on 1 April at 9pm and 8 April at 8pm, will follow the Scottish comedian as she sails on a 12-night Canary Islands cruise.
In the programme, Calman sails from Southampton to visit the islands of Gran Canaria, Tenerife and Lanzarote, before heading to Madeira and the Spanish port of Vigo.
Onboard the Medallion-class vessel, Calman tries her hand at cocktail flairing, gets involved with flower arranging for a wedding at sea, enjoys a pampering session and serves afternoon tea in The Sanctuary.
The 3,560-guest Regal Princess sails around the Mediterranean and Greek Isles from March to November 2022, with departures from Athens, Barcelona and Rome.
Tony Roberts, vice president of Princess Cruises UK and Europe, said: "We’re looking forward to viewers following Susan Calman as she enjoys everything a Princess cruise has to offer.
"And for those who would like to experience the same voyage that Susan travelled on, both Enchanted Princess and Sky Princess are offering Canary Islands itineraries round-trip Southampton this year."
