Lisa Henning, managing director of Inspire Europe, said the group has a "great deal of experience in this area", having handled the travel arrangements for other charities for the past eight years.
"We couldn’t be more delighted that the Family Holiday Charity has chosen us as one of their trusted travel partners," Henning continued.
"There is a great cultural fit between our two organisations, and we have already formed a great working relationship with their team.
"Our team is highly trained and very experienced in dealing with often highly personalised travel plans, and we feel honoured to be entrusted in managing this important role with those travelling on grants provided by the charity."
Formerly known as the Family Holiday Association, the Family Holiday Charity unveiled a new name and visual identity earlier this year.
The charity supports families facing tough times by offering them holidays and short breaks in the UK.
Kat Lee, chief executive of the Family Holiday Charity, said: "Working with trusted and accredited travel partners like Inspire means that the Family Holiday Charity team can spend more time focusing on what matters – the families we’re here for and their holiday experience."