The vessel, which will be powered by liquefied natural gas, will sail from Southampton on 7 August around the coast of its island namesake and the Scottish Isles.
Hadley is known for chart-topping singles such as ’True’, ’Gold’ and ’Through the Barricades’.
A "kaleidoscopic" firework display, from the island of Iona, will take place alongside aerial shows devised by Canadian entertainment company Creativiva.
Marco Pierre White and Olly Smith will offer food and drink "masterclasses" on board the 5,200 guest vessel.
P&O president Paul Ludlow said Iona’s maiden voyage will be a "momentous milestone" for travel.
"It is apparent that Iona’s maiden voyage is to the ship’s namesake island which has been the inspiration for many elements on board – the sense of space in the SkyDome through to the heather in our Marabelle gin distilled on board," he added.
"Booking demand is strong so we know how eager our guests are to holiday on Iona. We are immensely proud of this ship and are excited for guests to experience it for themselves."
After an inaugural season of UK coastal cruises Iona will offer holidays to Spain and the Canary Islands from September 2021. 14-night holidays are available from £1,299 per person.
