Virgin Atlantic will launch three new routes to Pakistan later this year.
Virgin will fly from Heathrow to Lahore and Islamabad, and from Manchester to Islamabad.
Seats will go on sale in September, subject to regulatory approval, with flights due to get under way in December.
Three classes will be available – Upper, Premium, and Virgin’s three-tier Economy class (Light, Classic and Delight).
The airline said the move came in response to "large, fast-growing demand" for VFR travel from customers in the UK, as well as in the US.
Virgin said US travellers will be able to connect via Heathrow from New York, Los Angles and several other major US cities, while connections to European destinations will be available through Virgin’s codeshare and interline partners.