The line will station Disney Dream in Southampton, where it will sail a series of three-, four- and seven-night voyages.
These will head to northern Europe and Norway’s fjords, taking in the village of Olden, Denmark’s capital Copenhagen and Portland in Dorset.
Early booking will get under way for Disney Cruise Line Castaway Club members on Monday (10 February), with general sales opening a week later on 17 February.
Each voyage will feature Disney’s signature entertainment, dining options and service proposition.
Prior to heading to the UK, Disney Dream will sail transatlantic from Fort Lauderdale to Barcelona, and make a maiden call in Cagliari on Sardinia.
In Europe, it will sail seven- and 12-night cruises from Barcelona and Rome (Civitavecchia) visiting Med destinations in Italy, Greece, Spain, Malta and France, including Santorini and Rhodes.
Disney will also station three ships in Florida, sailing to the Bahamas and the eastern and western Caribbean, including stops at Disney Castaway Cay and Disney Lookout Cay.
Elsewhere, Disney Adventure will sail ex-Singapore in December 2025, featuring three new Marvel-themed attractions and a Broadway-style musical. The line will also operate another ship – a second – from Alaska.