Second doses are currently being administered to more than 3,500 employees in the sector.
According to a survey carried out by the Antigua and Barbuda Hotels and Tourism Association (ABHTA), around 45% of the twin islands’ accommodation is booked for October to December 2021.
The ABHTA said there was "potential for growth", pointing towards the possibility of the UK government placing the destination on its green list over the coming months.
The US Centers for Disease Control and Prevention has already given Antigua & Barbuda level one status, opening up travel to the destination.
Vernon Jeffers, executive chairman of the ABHTA, said: "We must be serious and think aggressively about promoting our destination as sun, sea and safe.
"Safety means ensuring we protect our employees and encourage them to get vaccinated, protecting themselves and their families.
"Our team members must also feel safe in a work environment where they can deliver the best service to guests. Our success is simply vaccination, where each one, protects the other."
