The agency tweeted health secretary Matt Hancock and prime minister Boris Johnson offering its services.
It came after Scottish brewery firm BrewDog made a similar pledge to Hancock and Scotland’s first minister Nicola Sturgeon.
"Incredible idea. We’d love to offer up our shops too," tweeted the agency.
"Our stores are going unused right now, and with back-of-house kitchens, fridges and plenty of space, we reckon they’d be the ideal vaccination space. We want to help with the rollout."
Flight Centre’s offer also comes as the UK prepares to roll out the Oxford University and AstraZeneca coronavirus vaccine from Monday (4 January).
