Multi-branch agency Go Travel has ceased trading.
The company, which had four branches, in Blackheath, Chislehurst, Petts Wood and Locksbottom, posted on its website today: "Nowhere to Go.
"After 21 years of a great family business Go Travel has ceased trading, due to falling victim of the Covid-19.
"Since the beginning of lockdown in March we have tried all means possible to keep our business running and all our staff employed during this very difficult time.
"Our staff have been amazing, working from home, agreeing to cut their hours.
"Unfortunately, after exhausting all avenues trying to survive, the family had to make the awful, heart wrenching decision to close its doors.
"It’s a very sad day, as we know we are not alone, many many others are in the same position as us, who knows how long Coronavirus will keep tightening its hold on the travel industry.
"We are very lucky and thankful to have had such a loyal client base and fantastic staff for so many years."
The majority of holidays sold by Go Travel were sold as an agent for other tour operators.
Go Travel also sold a small number of Atol protected flight-inclusive packages and a small number of package holidays which did not include flight, which are protected by Abta.
Julia Lo Bue-Said, chief executive of Advantage Travel Partnership, of which Go Travel was a member, said: "A desperately sad day for all the staff, family and customers of Go Travel.
"A business that has done all it could to survive the pandemic but against a back drop of blanket quarantine measures, border restrictions and a systematic failure on the governments part to recognise that the travel industry requires sector specific support, this 21 year old business was simply unable to trade any longer."
More information on the collapse can be found on the Abta website.