Flybe franchise partner Blue Islands will operate the new routes to Southend and Liverpool.
Its daily Southend service will launch on May 20.
A twice-weekly Liverpool service, Tuesdays and Saturdays, will start on May 21.
Fares for both routes will lead in from £29.99 one way.
Rob Veron, Blue Islands chief executive, said the announcement demonstrated the airline’s commitment to the Channel Islands.
“We know locally there is a shared aspiration for more air links from Guernsey, particularly alternatives to London and believe this extra connectivity combined with our lowest fares is positive news for residents and also means increased visibility for Guernsey in new UK markets where potential new visitors now have easy access to our island,” Veron added.
