The comedian, writer and presenter will board Eurodam in Fort Lauderdale for a 10-night Panama Canal Sunfarer voyage.
During the first of two episodes, Calman will visit HAL’s private Bahamian island of Half Moon Cay, then call into the Dutch Caribbean islands of Aruba and Curacao. Episode two, which airs on 6 May, will feature the Panama Canal and Costa Rica.
Lynn Narraway, managing director UK and Ireland for HAL, said: "We are absolutely delighted to have Susan visit Half Moon Cay during our 25th anniversary year of Holland America Line acquiring this tropical paradise.