Holidays can be booked with all ITC brands, including Inspiring Travel, Rainbow, Regent, and sporting operator Spectate.
The company will look to support agents in the region with a trade toolkit, an agent sales team for Inspiring Travel and a dedicated trade Facebook group to keep agents updated with the latest news.
Trade partnership director for Inspiring Travel Di Selby said: "We’re delighted to be expanding into the Irish market and to build relationships with new agent contacts.
"We are passionate about travel and we have a quality offering from all our brands that sit under the ITC quality kitemark."