The incident, which happened on Sunday (27 August), saw the cruise ship break free from its moorings during a storm in Mallorca and collide with a freight vessel.
P&O said a small number of people are being cared for onboard after sustaining minor injuries, and according to the BBC, around 321 passengers were told they would have to fly home due to structural damage to a lifeboat.
"Following a weather-related incident in Palma de Mallorca on 27 August, P&O Cruises Britannia departed Palma last night and is expected to reach Southampton on Friday morning," a spokesperson told TTG.
Following the incident, Lisa Henning, managing director of the Inspire Group, urged travel companies to improve communication with agents and operators.
