The budget carrier will launch flights to the Lithuanian capital from Birmingham and Liverpool in October.
A three-times-weekly Birmingham-Vilnius service will get under way on 22 October, flying on Tuesdays, Thursdays and Saturdays.
Two days later, Wizz will launch a twice-weekly Liverpool-Vilnius service, operating on Tuesdays and Saturdays.
Flights will be operated by a new Airbus A320ceo aircraft Wizz is basing in Vilnius.
Fares lead in from £21.99pp.
Wizz has also restored its twice-weekly Luton-St Petersburg (Pulkovo) service, flying on Wednesdays and Fridays, and announced a new Birmingham-Riga route.
It comes after Wizz also announced 11 new routes across two new single-aircraft bases at Doncaster Sheffield and Gatwick airports.
