Malaga will be the setting for the event, which will be staged over 8-10 June, ITT revealed at WTM London on Wenesday (5 November).
The conference will be held at the five-star Higueron Hotel Malaga, part of Hilton's Curio Collection.
Benidorm hosted the last ITT conference to be held in Spain, some 15 years prior.
The conference will comprise impactful business sessions, networking opportunities and social experiences.
Early-bird registration is now open; places for member delegates cost £595, rising to £695 for non-members.
Room rates at the Higueron Hotel Malaga start from €240 a night, including breakfast and local taxes, with this rate available to delegates for the three days before and after the conference.
Arturo Bernal, Andalucia's regional minister for tourism and external affairs, said: "Hosting this important event is both a privilege and a recognition of our region’s enduring charm, hospitality and commitment to excellence as a travel destination.
"This occasion also represents a wonderful opportunity to further strengthen the historic ties of friendship and collaboration that have long united the United Kingdom and Andalusia. We look forward to sharing the magic of our land with all participants."