The group said Ioannou's appointment would further strengthen its presence across two of its "most strategically important" international markets.
Ioannou brings more than a decade of industry experience from working in the Greek and wider Mediterranean hospitality sector, during which time he has built expertise in business development, strategic account management and market growth.
In his new role with Mayor, Ioannou will work closely with agents, operators, travel trade professionals and distribution partners to develop new strategic partnerships.