Oundle Travel director Paula Cockcroft said the company has faced "unforeseen circumstances" when its landlords reneged on a newly agreed lease "without prior warning".
"They proposed a 45% increase in our annual rent which was dishonourable and unacceptable," she said in a statement posted to the firm’s website.
"I have taken the decision to close Oundle Travel with immediate effect. I would like to take this opportunity to extend my sincere thanks to everyone who has loyally supported my business over the years.
"After a career of 41 years in the industry, I have decided to take this opportunity to retire."