The new offering covers Peru, Ecuador, the Galapagos Islands, Argentina, Chile, Brazil and Costa Rica.
A seven-night cruise with Star Clippers visiting Costa Rica and Nicaragua starts from £2,899pp.
Gaynor Atherton, senior business development manager for Latin Routes, reported a "sharp rise" in cruise requests from its agent partners.
"We’ll look after the clients from beginning to end to include flights and pre and post itineraries that really compliment the cruises that we can offer," Atherton added.