The carriers’ services to Amsterdam and Paris will operate from the new facility from tomorrow (Tuesday 28 September).
The latest additions mean more than a dozen airlines are now operating from the terminal, including long-haul carriers Singapore Airlines and Qatar Airways and leisure airlines Jet2.com and Tui Airways.
Passengers with Manchester airport car park or lounge bookings will have them transferred and be notified accordingly.
Manchester restaurant San Carlo opens its first airport location in Terminal Two on Thursday (30 September), followed by coffee shop Pot Kettle Black on Monday 4 October.
The airport’s managing director Karen Smart said: “It is brilliant to see yet more valued airline partners serving passengers through our new state-of-the-art facility and I’d like to take this opportunity to welcome KLM and Air France to Terminal Two.
“Plus, we’re delighted to see two further Manchester brands, San Carlo and Pot Kettle Black, open their doors to passengers. Feedback for the new terminal has so far been incredibly positive, and we cannot wait for more and more passengers to experience it.”