It follows the ousting of former Peruvian president Pedro Castillo last month, which saw widespread protesting and blockades disrupt travel to and around the country.
Hundreds of tourists found themselves stranded at Machu Picchu and on the Inca Trail owing to a suspension of rail service from Cusco and flights to the city.
Many of the country’s regional airports have now reopened, but a fresh wave of protests in capital Lima and across the south of the country got under under way on Wednesday (4 January), prompting the FCDO to renew its guidance to travellers – warning them that travel to some parts of the country "may not be possible".
Rail services to Machu Picchu have once again been suspended.
"Political protests in southern Peru and Lima started on 4 January," said the FCDO. "They can easily spread to other parts of the country. These protests are unpredictable and can escalate quickly and include violence.
"You should take particular care to avoid all areas of protests. If possible, you should remain in a safe place. You should also monitor local media, including social media channels.
"Travellers arriving in Lima should be aware that travel to some parts of the country may not be possible. Protests may cause travel disruption, including with road blockades, suspension of train services and airport closures in different parts of the country.
"Train services to Machu Picchu have been temporarily suspended since 4 January. Travellers should recheck with their airline or tour operator and revisit travel plans ahead of any travel."
The FCDO is advising travellers to fill out a form provided by the Peruvian government to identify any visitors experiencing travel difficulties and disruption as a result of the protests.