NHS, social care workers, emergency services staff and armed forces employees were invited on free cruises with Royal throughout the summer in recognition of their "tremendous efforts" over the last year during the Covid pandemic.
Anthem will embark on a selection of four-night ocean sailings and five to eight-night British Isles itineraries from Liverpool and Belfast to Kirkwall in Scotland.
Ben Bouldin, Royal’s vice-president EMEA, said it was an "honour" to host some of the country’s key workers.
"It’s thanks to these individuals, who have worked so hard to see our country through this tough time, that this moment is finally here," he added.
"I have no doubt they will have an incredible and well-deserved break aboard our UK-favourite, Anthem of the Seas."
