Chief operating officer Jonathan Woodall-Johnston confirmed the deal was agreed earlier this month after Hays approached Ryanair following boss Michael O'Leary's change of heart about working with the travel trade.
It means Hays agents can now offer Ryanair flights when creating dynamic packages for their clients, offering greater flexibility when booing city breaks, in particular.
The move brings the agency into line with some of travel's biggest names including Tui, On the Beach and Loveholidays, which have signed distribution deals allow them to package Ryanair flights.
