The founder of Virgin Atlantic said if the UK cut ties with the EU, it would be a "very, very, very, very sad day".
"I think it would be the start of most likely the breakup of the European Union,” he added.
Branson also told Sky News he believed a Brexit “would be very, very damaging for Great Britain”.
He added that he hoped “sense prevails” when it comes to the referendum.
Branson highlighted the fact that there had not been any wars within the EU bloc since World War Two.
"The European Union has managed to avoid any wars within the European Union since the Second World War," he said.
Branson: A Brexit would be 'very very damaging for Great Britain'
Sophie Griffiths
22 February 2016
Sir Richard Branson has warned that if Britain votes to leave the European Union it could trigger the end of the European Union.
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