Around 30 airlines including Qatar Airways will move to the reopened terminal to allow for more check-in space and stand capacity, freeing up space at other terminals.
Local buses, the Piccadilly Line and the Elizabeth Line with operate into the terminal from 14 June.
The airport said its plans to reopen were on track and announced intentions to recruit up to 1,000 security officers and support staff to aid the process.
Heathrow’s customer service team will also be bolstered to help manage queues at check-in during the peak summer months, as well as a mobilisation of senior managers across terminals to assist passengers.
A range of retail, food and beverage outlets will be available at Terminal 4 with more expected to open later in the summer.
The airport said while the terminal was closed it took the opportunity to refurbish toilets, air conditioning and hold baggage machines.
Heathrow chief executive John Holland-Kaye, said: “While we are still years away from passenger numbers returning to pre-pandemic levels, reopening Terminal 4 will give airlines at Heathrow extra space across the airport, helping them manage the impact additional travel documents continue to have on check-in times.