The airport, part of Manchester Airports Group, will work with Fulcrum BioEnergy Limited UK, which is developing a new refinery for sustainable aviation fuel (SAF) in nearby Cheshire.
Under the deal, SAF will be supplied to Manchester airport through an existing pipeline running between the Fulcrum NorthPoint refinery at Stanlow and the airport.
This type of sustainable fuel can be blended with traditional aviation fuel so that it can be used to power existing aircraft and cut emissions.
Neil Robinson, MAG’s CSR and airspace change director, said: “Today really is a landmark moment in our journey towards a decarbonised aviation sector.