The route will operate out of Gatwick and Manchester airports, starting May 2019. It will run once a week every Saturday from both airports.
Tui says the move offers British holidaymakers exclusive access to the so-called “toe of the boot” on Italy’s southernmost peninsula, it becoming the first tour operator to sell holidays to Calabria.
Calabria is known for its food, culture and extensive coastline.
Besides the new flights, Tui will launch its first Tui Magic Life hotel in Italy in May 2019 to support the new route.